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statins

Obese and Smoking

DO STATINS BENEFIT HEALTHY PEOPLE ?

  by  Dr. Neville Wilson.    ( MODERN MEDICINE Vol 43, Number 2, 2013 – The Irish Journal of Clinical Medicine)   Statins are inhibitors of the enzyme (HMG-CoA) reductase, which catalyses the rate limiting step in cholesterol formation, reducing total and low-density lipoprotein (LDL) cholesterol concentrations, but also inhibiting …

Tredaptive

THE RISE AND FALL OF TREDAPTIVE

by Dr. Neville Wilson 30 Jan 2013   Tredaptive was introduced into the European drug market on 3rd July 2008, as a pharmaceutical formulation designed to treat certain forms of mixed  dyslipidaemia in patients judged to be at risk of cardiovascular disease. On the basis of well established cardiovascular benefits of …

HDL particle

HIGH DENSITY LIPOPROTEIN – HIGHER IS BETTER

by   DR. NEVILLE WILSON. PREAMBLE: Coronary Heart Disease (CHD) remains the leading cause of death in the Western World.  Yet, despite the documented decrease in cardiac-related mortality since the late 1960s, the incidence of CHD has not declined in recent years. (1) Data from EUROASPIRE III shows that primary strategies …

"high cholesterol in older folks is a friend and not a foe" - Dr Nev (image from guardian.co.uk)

POOR TED, YOUR CHOLESTEROL IS TOO LOW !

“Ted 70, loves paintball. A month ago his cholesterol was 5.1. It’s well below that now “ So reads the announcement in an advert which proudly promotes the cholesterol lowering power of it’s popular dietary product. (Sunday Independent 1 July, 2012.) Having reportedly consumed the widely marketed plant sterol containing …

False Claims of Benefit in Cholesterol Trials

     In the pre-statin era of the 1970-1980s many trials were conducted in an attempt to prove the validity of the “lipid hypothesis”, the theory that dietary fat and cholesterol were causative in heart disease, and that reductions in dietary and blood cholesterol would translate into reductions in risk for …

High Cholesterol Reduces Risks in Elderly

The traditional view regarding cholesterol and its impact on health and longevity is the perception of an associated increase in risk, with recommendations to reduce such risk by reducing blood cholesterol levels with a cholesterol lowering agent. (a statin drug).   Contrary to this widespread and popular perception, is the …

THE ANTI-AGING PROPERTIES OF CARNOSINE

It is generally recognised that many disease processes, as well as the process of natural ageing, are caused by the formation of free radicals, a by-product of oxidation within the cells of our several body tissues. What is not well known is that another process, which irreversibly alters the normal …